Brightening and rejuvenating senolytic day cream SPF25 pH 4.5 with peptide tyrosinase inhibitors against hyperpigmentation and accelerated aging.
It has strong hyperpigmentation-brightening properties, reduces redness and signs of inflammatory changes and evens out skin tone. The formulation contains a system of two synergistically acting skin brightening and anti-inflammatory whitening peptides – effective for inhibiting the melanogenesis pathway and the formation of pigmentary lesions. Effectively inhibits tyrosinase activity and ultimately melanin. At the same time, it has a senolytic action to reduce inflammation and rejuvenate the skin. Eliminates senescent ageing cells, so-called ‘zombie cells’ that cause inflammation and degradative damage, including collagen damage. It counteracts accelerated ageing, strengthens the skin barrier, increases elasticity and gives deep hydration. Thus, it has a holistic regenerative and protective effect on the skin.
The cream is designed for skin with hyperpigmentation, uneven skin tone and photo-ageing – dry, vascular, with symptoms of premature ageing and photo-ageing and mature skin with wrinkles.

Most important active ingredients.
✓ Melan Inhibitor 2-Peptide System – is a combination of two whitening peptides with exceptional efficacy confirmed by clinical studies. They have the effect of brightening the skin by inhibiting melanogenesis pathways and an anti-inflammatory action against environmental stimuli such as UV radiation.
✓ Senolytic Proteome Youth Extract eliminates senescent pro-inflammatory “zombie cells” that accelerate the ageing of other skin cells. At the same time, it protects skin proteins from oxidative damage and its effects such as redness, signs of inflammatory changes and accelerated ageing with collagen degradation.
✓ Nisinoxid® is a peptide antimicrobial and antioxidant system with rejuvenating and regenerative properties that enhances the protection of the microbiome and skin barrier.
✓ Stable vitamin C (SAP) whitens, promotes antioxidant and anti-ageing protection, and soothes, hydrates and strengthens capillaries.
✓ Complex Allantoin VC combines the whitening, antioxidant and anti-ageing effects of vitamin C with the soothing and moisturising effects of allantoin.
✓ Turmeric and bearberry extracts have anti-inflammatory, anti-bacterial and antioxidant properties to lighten discolouration and skin tone.
✓ Hyaluronic acid with different molecular weights gives maximum hydration, smoothing and protection at all levels, from the surface to the deepest layers of the skin. The holistic action against skin ageing and hyperpigmentation strengthens the skin’s condition and protection against damage of various origins that accelerate and aggravate adverse symptoms.
[frame colour=”gold”]The slightly acidic pH of the product strengthens the skin’s protective barrier against pathogens (harmful bacteria, fungi, moulds), stimulates anti-inflammatory protection and enzyme economy. It is the first protection against bacteria, the effects of UV radiation and environmental pollution (dryness, collagen damage, wrinkles, discolouration). The holistic action against skin ageing and hyperpigmentation strengthens the skin’s condition and protection against damage of various origins that accelerate and aggravate adverse symptoms. [/frame].
Agemelan Holistic gives a holistic effect of skin renewal, reducing hyperpigmentation and evening out skin tone.
Indications
- pigmentation of various origins, including post-sun spots, hormonal hyperpigmentation, melasma, freckles
- Any skin type with uneven skin tone and signs of photoageing
- Loss of radiance.
- loss of radiance and vitality, visible deterioration of the skin
- Grey, dull, flabby skin with no energy
- Skin that is not well-defined
- exposure to oxidative stress
- exposure to UV radiation and environmental pollution
- Also recommended before and after aesthetic medicine treatments against hyperpigmentation – laser therapy and dermatological peels
Effect
- reduction of pigmentation changes – hyperpigmentation and uneven skin tone
- stimulation of cellular cleansing – detoxification
- antioxidant, anti-inflammatory and anti-ageing effects
- restoration of skin structures whose damage causes and exacerbates pigmentary changes
- strengthening the skin’s protective barrier against free radicals, bacteria and the effects of damage





Night cream pH 4.5 for acne blemishes and scars
Boost Night Cream with niacinamide and GABA acid
Reparative day cream SPF20 UVA/UVB with peptide growth factor EGF 












