Brightening and rejuvenating senolytic serum pH 4.5 with peptide tyrosinase inhibitors counteracts hyperpigmentation and accelerated aging.
The intensive serum has a powerful brightening effect on hyperpigmentation of various origins by inhibiting the main melanogenic pathways. It contains a system of two synergistically acting whitening peptides with brightening and anti-inflammatory properties, effective for inhibiting the melanogenesis pathway and the formation of pigmentary lesions. It effectively inhibits tyrosinase and melanin activity. At the same time, it has a senolytic effect for reducing inflammation and rejuvenating the skin. Eliminates senescent senescent cells so-called ‘zombie cells’ causing inflammation and degradation damage – including collagen damage. The serum enhances the protection of the structure of proteome-forming proteins against damage by reactive oxygen species (carbonylation).
The serum is designed for skin with hyperpigmentation, uneven skin tone and photo-ageing – dry, vascular, with symptoms of premature ageing and photo-ageing, and mature skin with wrinkles. It has a very well absorbed texture, essential and at the same time light.

Most important active ingredients
✓ Melan Inhibitor 2-Peptide System – is a combination of two whitening peptides with exceptional efficacy confirmed by clinical studies. They have the effect of brightening the skin by inhibiting melanogenesis pathways and an anti-inflammatory action against environmental stimuli such as UV radiation.
✓ Senolytic Proteome Youth Extract eliminates senescent pro-inflammatory “zombie cells” that accelerate the ageing of other skin cells. At the same time, it protects skin proteins from oxidative damage and its effects such as redness, signs of inflammatory changes and accelerated ageing with collagen degradation.
✓ Nisinoxid® is a peptide antimicrobial and antioxidant system with rejuvenating and regenerative properties that enhances the protection of the microbiome and skin barrier.
✓ Vitamin C (SAP, ascorbic acid) has powerful antioxidant, brightening and vascular strengthening properties. It protects the skin from photodamage and provides a beautiful and healthy appearance.
✓ The Allantoin VC complex combines the whitening, antioxidant and anti-ageing effects of vitamin C with the soothing and moisturising effects of allantoin.
✓ Hyaluronic acid with different molecular weights gives maximum hydration, smoothing and protection at all levels, from the surface to the deepest layers of the skin. The holistic action against skin ageing and hyperpigmentation strengthens the skin’s condition and protection against damage of various origins that accelerate and aggravate adverse symptoms.
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The slightly acidic pH of the product strengthens the skin’s protective barrier against pathogens (harmful bacteria, fungi, moulds), stimulates anti-inflammatory protection and enzyme economy. It is the first protection against bacteria, the effects of UV radiation and environmental pollution (dryness, collagen damage, wrinkles, discolouration). The holistic action against skin ageing and hyperpigmentation strengthens the skin’s condition and protection against damage of various origins that accelerate and aggravate adverse symptoms.
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Agemelan Holistic gives a holistic effect of skin renewal, reducing hyperpigmentation and evening out skin tone.
Indications
- pigmentation of various origins, including post-sun spots, hormonal hyperpigmentation, melasma, freckles
- Any skin type with uneven skin tone and signs of photoageing
- Loss of radiance.
- loss of radiance and vitality, visible deterioration of the skin
- Grey, dull, flabby skin with no energy
- Skin that is not well-defined
- exposure to oxidative stress
- exposure to UV radiation and environmental pollution
- Also recommended before and after aesthetic medicine treatments against hyperpigmentation – laser therapy and dermatological peels
Effect
- reduction of pigmentation changes – hyperpigmentation and uneven skin tone
- stimulation of cellular cleansing – detoxification
- antioxidant, anti-inflammatory and anti-ageing effects
- restoration of skin structures whose damage causes and exacerbates pigmentary changes
- strengthening the skin’s protective barrier against free radicals, bacteria and the effects of damage





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