Set for thermal lifting and skin contouring with neuroactive gamma-aminobutyric acid GABA and peptides.
A set of preparations for thermo-lifting and thermo-modelling treatments of the skin of the face and locally of the body. The treatments are performed with a thermoactive device for which the generated temperature does not exceed 70°C, e.g. Thermo-Spherix® or ThermoLED Master®
Thermo-Lifting is a thermo-lifting and thermo-modelling treatment for the face and locally the body.
Thermo-Lifting treatment kit
Includes two products for an in-office cosmetic treatment:
- Hermo-Lifting Serum (50ml) for application by massage. Intensely moisturising and modelling serum, smoothing wrinkles and stimulating the renewal of elastic fibres. Contains active ingredients aimed at rapid skin regeneration and rejuvenation, improving skin firmness and elasticity, stimulating collagen synthesis, strengthening the dermal-epidermal junction.
- GABA cream (50ml) – for thermo-active application. The cream is designed for professional thermoactive treatments – rejuvenating and shaping the skin of the face, neck and décolleté and locally of the body. The treatment is performed with cosmetic devices with heads for which the generated temperature does not exceed 70 degrees Celsius. It reduces skin flaccidity, strengthens and stimulates the renewal of elastin and collagen fibres, restores skin elasticity, firmness and resilience. Improves facial features, remodelling facial contours. Smoothes, reduces and fills in mimic wrinkles and deep furrows through a triple action system. The unique formula of selected active ingredients, gives rapid and visible skin rejuvenation. The cream contains an active anti-wrinkle concentrate – GABA wrinkle filler and silk proteins. It is a spectacularly rejuvenating concentrate with a unique formula and immediate and lasting wrinkle reduction .
Application: thermo-active treatment performed with a device for which the generated temperature does not exceed 70°C.
Recommendations and indications for the treatment
Zone: face, décolleté and selected parts of the body: bust, abdomen, buttocks, arms, hands:
Facial indications:
- lost elasticity, firmness
- flaccid, thinning skin
- dry, dry skin
- dry, dehydrated skin
- dry, dehydrated skin
- aging wrinkles, including around the eyes
- skin in need of regeneration
- skin in need of regeneration
- effect of a drooping eyelid
- fat pads
- fatty pads at the cheekbones
- fatty pads at the cheekbones
Body indications:
- lost elasticity, firmness
- flaccid, thinning skin
- dry, dry skin
- dry, dehydrated skin
- stretch marks, scars and other imperfections
- skin in need of regeneration
Effects of the treatment
- volumetric rejuvenation and smoothing of the skin
- a non-surgical lifting with a visible wrinkle-flattening effect
- rebuilding of collagen and elastin structures and stimulation of the production of new elastin fibres
- improvement of skin density and elasticity
- improvement of skin density, elasticity and firmness
- improvement of the oval and normal skin tone
- stimulation of the skin’s natural regeneration, nourishment and oxygenation processes
- revitalization, improvement of blood circulation and colour
Most important active ingredient
✓ GABA gamma-aminobutyric acid (Gamma Amino Butyric Acid GABA) – a neuroactive rejuvenating ingredient for immediate and long-lasting wrinkle reduction and collagen renewal, hydration and skin barrier. Thanks to its small molecule, it has the ability to act quickly at the epidermal level as well as in the dermis. GABA relaxes facial wrinkles and crow’s feet by interacting with receptors, external nerve cells and smooth muscle cells, with the result that skin cells shrink less and are more relaxed, fine lines and wrinkles become less visible and the skin quickly begins to look younger – the first effects of wrinkle reduction according to studies are visible in as little as 10 to 30 minutes. At the same time, GABA stimulates the synthesis of hyaluronic acid and collagen and protects fibroblasts from free radical damage. It rebuilds the skin’s protective barrier, moisturises, reduces roughness and brightens skin tone. As a result, the skin is rejuvenated, hydrated, supple and with smoothed wrinkles.
Other active ingredients in the treatment
✓ Matrixyl 3-Peptide – an innovative very potent anti-wrinkle low-molecular-weight peptide stimulates the synthesis of 6 major components of the dermal matrix and dermal-epidermal junction (DEJ): collagen I, III, IV (and HSP47), laminin-5, fibronectin and hyaluronic acid. It improves the basic biomechanical parameters of the skin condition: skin hydration, density, firmness and elasticity, skin tone and facial oval, thus filling in wrinkles from within, including on the forehead as well as ‘crow’s feet’, producing a visible effect of smoother and fuller skin.
✓ Synpept 2-Peptide – low-molecular peptide complex (dipeptide) with targeted anti-wrinkle, smoothing, skin elasticity-enhancing effects. It strengthens the Dermal-Epidermal Junction (DEJ Dermal-Epidermal Junction), which has the task of maintaining the cohesion of the dermis and epidermis layers. The main components of the DEJ are collagen fibres types IV and VII and XVII and laminin V, ensuring that the two layers adhere tightly to each other.
✓ Liposlim – is a combination of two high-purity plant molecules (phizetin and frambinone) that together prevent fat accumulation. Phizetin is a naturally occurring flavonoid isolated from Buxus sinica (Korean boxwood). Frambinone is a naturally occurring phenolic compound (obtained from aniseed, Pimpinella anisum), also known as raspberry ketone. The complex of these two plants significantly improves skin elasticity, smooths bumps and reduces swelling.
✓ High-molecular-weight hyaluronic acid (1MDa) – forms a protective film, increases moisture reserves, reduces transepidermal water loss (TEWL).

The latest offering among substances with anti-ageing effects is gamma-aminobutyric acid (GABA). It is a non-protein amino acid naturally present in the human body that plays a key role in regulating the vital activity of plant and animal organisms. It can reduce neuronal reactivity, smooth wrinkles, have a calming effect, reduce stress and facilitate sleep. As the years go by, the production of this amino acid in the human body decreases, which can lead to stronger feelings of stress, more fatigue or sleep problems. The most visible sign of the effects of stress, fatigue and sleep problems on our appearance is the greying of the skin, the loss of radiance, elasticity and resilience, and the formation of wrinkles.
Does gamma-aminobutyric acid affect the skin?
Both the skin and the human nervous system originate from the ectoderm of the embryo. Therefore, some receptors are shared by skin cells and nerve cells, including the GABA receptor. Researchers have shown that the enzyme responsible for the synthesis of gamma-aminobutyric acid is produced by human dermis fibroblasts. In the dermis, gamma-aminobutyric acid stimulates the synthesis of hyaluronic acid and collagen, protects fibroblasts from free radical damage, and thus maintains elasticity and adequate hydration levels. In the superficial layers of the epidermis, GABA receptors are found in the keratinocytes of the dermis. Externally applied gamma-aminobutyric acid aqueous solution induced a direct interaction between the GABA molecule and the GABA receptor (A). This interaction induced rapid restoration of the skin barrier and prevented hyperplasia of the dermis. These results suggest that gamma-aminobutyric acid and its receptor influence skin barrier homeostasis. An important advantage of gamma-aminobutyric acid is that, when delivered externally, it rapidly penetrates the skin. As a result, it quickly and effectively relaxes the muscles, reducing facial wrinkles and crow’s feet. As a result, the skin looks younger and fresher shortly after its application.
GABA Extreme Wrinkle Filler
GABA Extreme Wrinkle Filler contains gamma-aminobutyric acid obtained by biotechnology – through Lactobacillus fermentation and biotransformation processes. It acts on the GABA receptors of the skin cells, activating them. The chloride ion channel then opens up and helps the permeability of chloride ions across the cell membrane. This allows them to penetrate the nerve cells, causing hyperpolarisation of the cell membrane and inhibition of the nerve cells. As a result, skin cells contract less and are more relaxed. Fine lines and wrinkles become less visible and the skin quickly begins to look younger. A short-term study involving 30 healthy volunteers aged 25-50 years showed that gamma-aminobutyric acid used in concentrations above 1% could effectively reduce the depth of wrinkles. The higher the concentration, the faster the substance worked and the more visible and longer-lasting the effect was.





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