Brightening and rejuvenating, the pH 4.5 pethidium-senolytic serum reduces hyperpigmentation and prevents the formation of new ones, while slowing down the skin’s ageing process.
The highly concentrated serum has an effective action to lighten hyperpigmentation of various origins by inhibiting the main melanogenic pathways. It contains a system of two synergistically acting whitening peptides with skin brightening and anti-inflammatory effects, effective for inhibiting the melanogenesis pathway and the formation of pigmentary lesions. Effectively inhibits tyrosinase and melanin activity. The serum also has a senolytic effect for reducing inflammation and rejuvenating the skin. It eliminates senescent ageing cells so-called “zombie cells” that accelerate the ageing of other cells. “Zombie cells” cause inflammation and degradation damage – including collagen damage. The serum formula protects the structure of the proteome-forming proteins from damage caused by reactive oxygen species (carbonylation). Additionally, it visibly reduces redness and improves skin elasticity. It counteracts accelerated ageing, strengthens the skin barrier against cellular stress and oxidative damage including hyperpigmentation, increases elasticity and gives deep moisturisation. The serum is designed for skin with hyperpigmentation, uneven skin tone and photo-ageing – dry, vascular, with symptoms of premature ageing and photo-ageing and mature skin with wrinkles. It has a very well absorbed texture, essential and at the same time light.

Most important active ingredients.
✓ Melan Inhibitor 2-Peptide System – is a combination of two whitening peptides with exceptional efficacy confirmed by clinical studies. They have the effect of brightening the skin by inhibiting melanogenesis pathways and an anti-inflammatory action against environmental stimuli such as UV radiation.
✓ Senescent Proteome Youth Extract eliminates senescent pro-inflammatory cells so-called “zombie cells” that accelerate the ageing of other skin cells. This ingredient protects proteins from oxidative damage and its effects such as redness and signs of inflammatory changes. It slows down the process of accelerated ageing, collagen degradation and loss of elasticity.
✓ Nisinoxid® – a peptide antimicrobial and antioxidant system with rejuvenating and regenerative properties that enhances the protection of the microbiome and skin barrier.
✓ Hyaluronic acid with different molecular weights gives maximum hydration, smoothing and protection at all levels, from the surface to the deepest layers of the skin.
✓ Stable Vitamin C (SAP) thanks to its properties of inhibiting melanin synthesis and counteracting free radicals, helps protect the skin from photodamage for a beautiful and healthy appearance. ✓ The Allantoin VC complex combines the whitening, antioxidant and anti-ageing effects of vitamin C with the soothing and moisturising effects of allantoin.
✓ Turmeric and bearberry extracts have anti-inflammatory, anti-bacterial and antioxidant properties to lighten discolouration and skin tone.
✓ The active formula is complemented by antioxidant green tea extract, which enhances the skin’s protection against damage caused by pollution and premature ageing, and stimulates microcirculation and skin renewal.
✓ Bio-chromophores, of plant origin developed by Chantarelle experts, are components of light-sensitive preparations for PDT LASER or LED photodynamic therapies that have a special ability to absorb light of a specific wavelength. Applied to the skin area subjected to therapy, they accumulate laser light multiplying the energy reserve in the cell, thus maximising: the efficiency of metabolism and absorption of active ingredients contained in the preparations. The holistic action against skin ageing and hyperpigmentation strengthens the condition and protection of the skin against damage of various origins, which accelerates and aggravates adverse symptoms.
[frame colour=”gold”]The slightly acidic pH of the product strengthens the skin’s protective barrier against pathogens (harmful bacteria, fungi, moulds), stimulates anti-inflammatory protection and enzyme economy. It is the first protection against bacteria, the effects of UV radiation and environmental pollution (dryness, collagen damage, wrinkles, discolouration). The holistic action against skin ageing and hyperpigmentation strengthens the skin’s condition and protection against damage of various origins that accelerate and aggravate adverse symptoms. [/frame].
Application: biostimulating LLLT laser/LED light treatment, thermoactive treatment, sonophoresis or manually
The serum is designed for PDT LASER LLLT or LED treatments with 650 nm red light and 525 nm green light. The treatment can also be carried out using the THERMO thermal method with a device that generates temperatures up to 42 degrees C or by micro-needling up to 0.5 mm or by sonophoresis or manually.
Agemelan Holistic gives a holistic effect of skin renewal, reduction of hyperpigmentation and even skin tone.
Indications
- pigmentation of various origins, including post-sun spots, hormonal hyperpigmentation, melasma, freckles
- Any skin type with uneven skin tone and signs of photoageing
- Loss of radiance.
- loss of radiance and vitality, visible deterioration of the skin
- Grey, dull, flabby skin with no energy
- Skin that is not well-defined
- exposure to oxidative stress
- exposure to UV radiation and environmental pollution
- Also recommended before and after aesthetic medicine treatments against hyperpigmentation – laser therapy and dermatological peels
Effect
- reduction of pigmentation changes – hyperpigmentation and uneven skin tone
- stimulation of cellular cleansing – detoxification
- antioxidant, anti-inflammatory and anti-ageing effects
- renewal of skin structures whose damage causes and exacerbates pigmentary changes
- strengthening the skin’s protective barrier against free radicals, bacteria and the effects of damage





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